It also reduced slow-wave EEG activity (when one begins to fall asleep, EEG begins to slow) and decreased self-reported problems with mood and alertness. The drug lessened the effects of sleep deprivation in four of six flight maneuvers tested compared to the placebo.
#WAKE UP TIME PILLS SIMULATOR#
The pilots were then evaluated in helicopter simulator flights, resting electroencephalograms (EEGs), and mood questionnaires. They were given modafinil in one session and a placebo in the other. At the United States Army Aeromedical Research Laboratory in Fort Rucker, Alabama, six pilots were kept awake continuously for two forty-hour periods. The most common side effects in patients in clinical trials include headaches (1 percent), nausea (1 percent), depression (1 percent) and nervousness (1 percent).Ī June 2000 study published in Psychopharmacologia studied the drug's effects on people's abilities to accomplish demanding tasks despite a lack of sleep. "Unlike most wake-promoting drugs, it has very few side effects," says Tom Scammell, M.D., a sleep expert and an assistant professor in neurology at the Beth Israel Deaconess Medical Center in Boston. Modafinil mostly bypasses the downsides of staying up. When the drug wears off, it can lead to a rebound effect that causes extreme fatigue or depression. But aside from their addictive properties, they caused a range of side effects from agitation, irritability and nausea to increased heart rate, tics and impotence. One-quarter of adults have even taken sleep medication in the past year.īefore modafinil, the heavy-hitter stimulants of choice for those combating the urge to snooze have been amphetamines such as Dexedrine.
Although the average person needs about eight hours of sleep, adults get only an average of seven hours during the workweek, and 36 percent log less than 6.5 hours' sleep on weeknights.
The interest in sleep is not surprising in a country that does not get enough.
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